Table 1. Top 18 most enriched pathways by FINDSITE comb.
| Pathway | Enrichment factor | Number of proteins
in the pathway |
|---|---|---|
| Insulin signaling pathway | 77.5 | 67 |
| Alcoholism | 68.0 | 5 |
| Amphetamine addiction | 68.0 | 46 |
| Cocaine addiction | 68.0 | 42 |
| Huntington's disease | 68.0 | 36 |
| Amyotrophic lateral sclerosis (ALS) | 68.0 | 29 |
| GABAergic synapse | 68.0 | 28 |
| Taurine and hypotaurine metabolism | 68.0 | 27 |
| Proximal tubule bicarbonate reclamation | 67.3 | 14 |
| HMG-CoA reductase inhibitors | 59.8 | 4 |
| Galactose metabolism | 56.8 | 20 |
| Phosphotransferase system (PTS) | 54.1 | n.a. |
| Glycerolipid metabolism | 48.7 | 20 |
| Butirosin and neomycin biosynthesis | 45.9 | 3 |
| Glyoxylate and dicarboxylate metabolism | 45.9 | 18 |
| Alanine, aspartate, and glutamate metabolism | 45.6 | 27 |
| Glycolysis/gluconeogenesis | 39.7 | 30 |
| Retrograde endocannabinoid signaling | 39.6 | 23 |