Table 1.

Study subject characteristics.^a

Patient	Gender	Age at disease onset	Age at surgery	Psychiatric comorbidities	Education/job status	Familiarity
1	M	6	17	Anxiety disorder NOS, depression, OCD, PDD, previously hospitalized for suicidal ideation	Home-schooled, part-time job	ADHD, Asperger syndrome, dystonia, tic disorder (brother); depression, OCD, TS (father)
2	F	10	35	ADHD, anxiety disorder NOS, OCD, self-harm attempts	High school graduate, occasional jobs	/
3	M	7	17	ADHD, OCD	Home-schooled	N/A (patient adopted)
4	M	4	18	GAD, OCD	High-school honor student, part-time job	ADHD (father); anxiety NOS (multiple family members on both sides); mood disorder and TS (paternal grandfather); hoarding disorder (paternal grandmother)
5	M	6	46	Depression, resolved OCD	Full-time job	Tic disorder (father, son, brother)
6	M	9	27	Benzodiazepine and narcotics dependence	Full-time job	/
7	M	9	27	Depression, OCD	Unemployed	/
8	F	14	32	ADHD, bipolar disorder, PTSD, substance abuse, suicide attempts, borderline personality disorder	Employed	/
9	F	6	22	ADHD, single episode of major depression	Home-schooled, unemployed	/
10	M	12	27	Depression, dysthymia	College graduate, unemployed	Tic disorder (paternal great uncle)
11	M	4	27	OCD	College graduate, unemployed	Alcohol abuse, anxiety NOS (mother, sister, multiple family members on maternal side), depression (sister, multiple family members on both sides), tic disorder (father)

^aADHD = attention-deficit hyperactivity disorder; GAD = generalized anxiety disorder; NOS = not otherwise specified; OCD = obsessive compulsive disorder; PDD = pervasive developmental disorder; PTSD = post-traumatic stress disorder; TS = Tourette syndrome.