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. Author manuscript; available in PMC: 2017 Feb 23.
Published in final edited form as: Circulation. 2016 Jan 26;133(8):732–741. doi: 10.1161/CIRCULATIONAHA.115.018595

Figure 1.

Figure 1

Flow diagram showing VIPS cases of childhood AIS and trauma-visit controls included in the current manuscript. Case-control comparisons are based on assays of the acute blood samples in 326 cases and blood samples collected at time of trauma visit for 115 controls; collection of convalescent samples in the controls was not feasible. Assays of paired blood samples (acute and convalescent) were considered the gold standard for defining positive acute herpesvirus serologies amongst cases (as fully described in the methods). Collection of convalescent samples in cases was performed when feasible.