Table 4.

Multivariate model showing independent predictors of childhood AIS using all 326 cases of childhood AIS and 115 stroke-free trauma controls^*

	Model with LAMI Country			Model without LAMI Country
Characteristic	OR	95% CI	P-value	OR	95% CI	P-value
Acute herpesvirus infection†	1.9	(1.1, 3.6)	0.02	2.2	(1.2, 4.0)	0.007
Age
0–3 yrs	Ref			Ref
4–7 yrs	0.2	(0.1, 0.5)	<0.0001	0.2	(0.1, 0.5)	<0.0001
8–11 yrs	0.1	(0.05, 0.2)	<0.0001	0.1	(0.05, 0.2)	<0.0001
12–15 yrs	0.2	(0.1, 0.4)	<0.0001	0.2	(0.1, 0.4)	<0.0001
16+ yrs	0.5	(0.2, 1.5)	0.24	0.5	(0.2, 1.5)	0.25
Race
White	Ref			Ref
Black	2.6	(1.0, 6.6)	0.04	2.5	(1.0, 6.3)	0.05
Asian	0.8	(0.3, 2.0)	0.63	1.2	(0.5, 2.9)	0.62
Other/mixed/unknown	0.9	(0.5, 1.8)	0.78	0.9	(0.5, 1.7)	0.71
Residence
Urban	Ref			Ref
Suburban	3.8	(2.2, 6.6)	<0.0001	3.6	(2.1, 6.3)	<0.0001
Rural	2.7	(1.4, 5.2)	0.003	2.6	(1.3, 4.9)	0.004
LAMI country	9.6	(1.1, 85)	0.04

^*All variables in the logistic regression model are shown.

^†Positive IgM antibody titers to any herpesvirus; using acute blood samples only to allow case/control comparison

Ref=reference category; LAMI=lower and middle income