Table 5.
Sensitivity for detection of acute herpesvirus infection of algorithm based on single acute blood samples versus paired samples (gold standard) among 187 childhood AIS cases with paired samples
| Positive acute herpesvirus infection |
||||||
|---|---|---|---|---|---|---|
| Based on Single Sample |
Based on Paired Samples |
Sensitivity of Single Sample |
Specificity of Single Sample |
|||
| Herpesvirus | n | (%) | n | (%) | ||
| HSV 1 or 2 | 44 | (23.5) | 75 | (40.1) | 59% | 100% |
| VZV | 11 | (5.9) | 18 | (9.6) | 61% | 100% |
| CMV | 3 | (1.6) | 10 | (5.3) | 30% | 100% |
| EBV | 1 | (0.5) | 5 | (2.7) | 20% | 100% |
| Any herpesvirus | 49 | (26.2) | 85 | (45.5) | 46% | 100% |