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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: Methods. 2015 Aug 24;99:128–134. doi: 10.1016/j.ymeth.2015.08.014

Figure 5. Physiologic assessment of force generation by bioengineered smooth muscle constructs in response to vasoactive intestinal peptide.

Figure 5

Force of relaxation measurements were acquired by real time force generation measurements taken after stimulation of constructs with 1 µM VIP. A) Representative tracings of human pylorus SMC constructs are presented. Bioengineered human pylorus constructs relaxed in response to VIP averaging minimum forces of −228.8 µN (SEM±4.6). B) Human SI SMC constructs also relaxed in response to VIP averaging −208.6 µN (SEM±6.8). C) No significant differences were observed in the maximum force of relaxation between bioengineered human pylorus and SI constructs (n=3).