Skip to main content
. Author manuscript; available in PMC: 2016 Feb 25.
Published in final edited form as: Bioorg Med Chem. 2015 Aug 4;23(17):5282–5292. doi: 10.1016/j.bmc.2015.07.073

Table 3.

Effect of modification of region A of 1 on cardiomyogenesis in mESCs

graphic file with name nihms759725t3.jpg
R2 R8 X1 X2 X3 CM Fold-changea
65 2-MeO H N C N 2.5 ± 0.5
78 H H C C C 2.0 ± 0.3
82 H N(Me)2 N C C 3.7 ± 0.4
83 H NH2 N C C 2.1 ± 0.3
85 H H N N C 3.1 ± 0.5
a

Fold-change in cardiomyogenesis compared to vehicle (i.e., DMSO)-treated cells.