Fig. 1. Human 16p11.2 loci associated with autism spectrum disorder (ASD). (A) The approximate location of 16p11.2 loci within human chromosome 16 is indicated (red box), along with annotated genes located at the loci. (B) The 24 annotated human genes within the 16p11.2 region are matched with corresponding Drosophila homologs or most closely related genes. Human genes with Drosophila counterparts of weak homology (i.e. SPN) as well as those with no obvious homolog (i.e. MVP) were excluded from further analyses.