Fig. 7.

Release profiles of capsules for three different drugs with each capsule containing 300 mg melt-extruded granules (20–30 mesh and 10% drug loading in melt-extruded granules); USP paddle method at 100 rpm; 900 mL medium at 37°C; 0–2 h in 0.1 N HCl; 2–6 h in 50 mM phosphate buffer pH 6.8; 6–10 h in 50 mM phosphate buffer pH 7.4. Triplicate samples (black square) diclofenac sodium; (black circle) theophylline; (white square) 5-amino salicylic acid