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Pore Structure Characteristics of 5-ASA Granules (20% Drug and 80% Eudragit® FS, 20–30 mesh) Prepared with Different Processes
| Granules prepared by melt extrusion method | Granules prepared by compression method | |
|---|---|---|
| Medium pore diametera (pm) | 0.0186 ± 0.0003 | 0.0420 ± 0.0004 |
| Particle density (g/mL) | 1.2762 ± 0.0325 | 1.0936 ± 0.02855 |
| Porosity (%) | 4.2975 ± 0.0621 | 5.4163 ± 0.0872 |
aMedium pore diameter was calculated based on pore volume. Three samples were tested for each type of granules
