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Formulation Compositions of NS and Extrudate
| Formulation | Soluplus® | Kollidon® 30 | SLS | EFZ | |
|---|---|---|---|---|---|
| % (w/w) | % (w/v) for NS, % (w/w) for extrudate |
% (w/v) for NS, % (w/w) for extrudate |
% (w/v) for NS, % (w/w) for extrudate |
||
| NS | A | – | 1.0 | 0.5 | 2.0 |
| B | – | 1.0 | 0.5 | 4.0 | |
| Extrudate | A | 98.25 | 0.5 | 0.25 | 1.0 |
| B | 97.25 | 0.5 | 0.25 | 2.0 | |
EFZ efavirenz, NS nanosuspension, SLS sodium lauryl sulfate
