Table I.

List of Some Commercially Available Pharmaceutical-Grade Extruders (10)

Company	Extruder	Capacity (kg/h)	Screw diameter (mm)	Screw assembly
Thermo Scientific	Pharma mini-HME micro-compounder	0.01–0.2	Variable	Co- and counter-rotating
	11-mm parallel twin-screw extruder	0.02–2.5	11	Co-rotating multiple elements
	HAAKE MiniLab II micro-compounder	0.01–0.2	Variable	Conical co- and counter-rotating
	EuroLab 16XL	0.2–10	16	Parallel co-rotating
	HAAKE Rheomex PTW 16 OS	0.2–10	16	Parallel co-rotating
	HAAKE Rheomex PTW 24 OS	0.5–50	24	Parallel co-rotating
	HAAKE Rheomex PTW 100 OS	0.2–5	Variable	Conical counter-rotating
	Pharma 16 HME	0.2–5	16	Parallel co-rotating
	TSE 24 MC	0.2–50	24	Parallel co-rotating
Leistritz	Nano16	0.2–0.8	16	Co-rotating
	ZSE 18 HP PH	0.5–7	18	Co-rotating
	ZSE 27 HP PH	2–60	27	Co-rotating
	ZSE 40 HP PH	20–180	40	Co-rotating
	ZSE 50 HP PH	60–300	50	Co-rotating
Gabler	DE 40	5–100	40	Co-rotating
	DE 100	80–800	100	Co-rotating
	DE 120	80–800	120	Co-rotating
Coperion Brabender	ZSK 18–70 Twin-screw stand-alone	–	18–70	Co-rotating
	TSE 20/40	–	20	Co-rotating

HME hot-melt extrusion