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PXRD profiles from samples stored at 40°C/43%RH for 6 months (from bottom to top) of GRIS crystalline drug (
), HME processed dispersions (
), and KSD processed dispersions (
) (from 10% to 40% drug load) in a (PVP K17) and c (HPMC E5). KSD processed dispersions of PVPK30 (
) and PVP K90 (
) (from 10% to 40% drug load) in b, and KSD processed dispersions of HPMC E15 (
) and HMPC E50 (
) (from 10% to 40% drug load) in d. Areas of observed trace crystallinity are marked with arrows
