Table V.

Appearance of Processed Batches

Drug load (%)	Polymer	Process	Color	Clarity	Porosity
10	PVP K17	HME	Yellow	Transparent	−
20	PVP K17	HME	Yellow	Transparent	−
40	PVP K17	HME	Yellow	Opaque	−
10	HPMC E5	HME	Dark brown	Transparent	−
20	HPMC E5	HME	Dark brown	Transparent	−
40	HPMC E5	HME	Brown	Opaque	−
10	PVP K17	KSD	Off-white	Opaque	+
20	PVP K17	KSD	Off-white	Opaque	+
40	PVP K17	KSD	Off-white	Opaque	+
10	PVP K30	KSD	Light brown	Opaque	+
20	PVP K30	KSD	Light brown	Opaque	+
40	PVP K30	KSD	Light brown	Opaque	+
10	PVP K90	KSD	Light brown	Opaque	+
20	PVP K90	KSD	Light brown	Opaque	+
40	PVP K90	KSD	Light brown	Opaque	+
10	HPMC E5	KSD	Light brown	Opaque	+
20	HPMC E5	KSD	Light brown	Opaque	+
40	HPMC E5	KSD	Light brown	Opaque	+
10	HPMC E15	KSD	Light brown	Opaque	+
20	HPMC E15	KSD	Light brown	Opaque	+
40	HPMC E15	KSD	Light brown	Opaque	+
10	HPMC E50	KSD	Light brown	Opaque	+
20	HPMC E50	KSD	Light brown	Opaque	+
40	HPMC E50	KSD	Light brown	Opaque	+

PVP polyvinylpyrrolidone, HPMC hydroxypropyl methylcellulose, HME hot-melt extrusion, KSD KinetiSol® Dispersing