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Taste Scores Given by Each Individual to Physical Mixture and HME Formulation for Griseofulvin
| Amount (mg) of API in 2 mL water | Volunteers | |||||||
| 1 | 2 | 3 | 4 | 5 | 6 | |||
| Water (no API) | – | – | – | – | – | – | ||
| 20 | – | 1 | 1 | 0 | – | 1 | Threshold of the subjects is in this range | |
| 40 | 1 | 2 | 3 | 2 | 1 | 2 | ||
| 80 | 2 | 4 | 3 | 5 | 2 | 4 | ||
| 150 | 4 | 4 | 5 | 5 | API equal to that in test formulation | |||
| Product testing (1 g powder/granules) equivalent to 150 mg of GRI | Average | Standard Deviation | ||||||
| Physical mixture | 4.5 | 2 | 4 | 4 | 5 | 5 | 4.08 | 1.11 |
| HME granules | 1 | 2 | 2 | 1.5 | 2 | 0.5 | 1.5 | 0.63 |
