Table 3.

Recent metaanalises of studies of n-3 poly-unsaturated fatty acids in post-operative atrial fibrillation

Ref.	Clinical setting	NO. of studies and of patients	Results
Costanzo et al[26]	POAF	8 RCTs/2687 pts	AF reduction
Benedetto et al[27]	POAF	431 pts	No AF reduction; at meta-regression analysis: Trend toward a benefit from PUFA for administration of EPA/DHA ratio = 1:2
Zhang et al[28]	POAF	8 RCT/2687 pts	No AF reduction
Ali-Hassan-Sayegh et al[29]	POAF	23 RCTs/4278 pts	AF reduction

RCTs: Randomized controller trials; pts: Patients; PO: Post-operative; AF: Atrial fibrillation; PUFA: Poly-unsaturated fatty acids; EPA: Eicosapentaenoic acid; DHA: Docosahexaenoic acid.