Table 1.
Interventional and randomized ongoing clinical trials on the use of hydralazine and procainamide in cardiovascular diseases
| No. | Status | Condition | No. of enrolled patients | Intervention |
| NCT00684489 | Completed | Hypertension | 52 | Hydralazine and other drugs |
| NCT02305095 | Not open for participant recruitment | Heart failure | 500 (estimated enrollment) | Hydralazine in combination with isosorbide dinitrate |
| NCT00661895 | Completed | Hypertension | 99 | Hydralazine and other drugs |
| NCT00599235 | Completed | Hypertension | 30 | Hydralazine, sildenafil, and placebo |
| NCT00223717 | Recruiting participants | Hypertension | 160 (estimated enrollment) | Hydralazine and other drugs |
| NCT01255475 | Completed | Heart failure, cardiac failure, and congestive heart failure | 21 | Hydralazine/amlodipine and placebo |
| NCT01516346 | Recruiting participants | Heart failure and congestive heart failure | 54 (estimated enrollment) | Hydralazine, isosorbide dinitrate, and placebo |
| NCT01822808 | Recruiting participants | Acute heart failure and left ventricular dysfunction | 500 (estimated enrollment) | Hydralazine, isosorbide dinitrate, and placebo |
| NCT00000499 | Completed | Cardiovascular diseases, heart diseases, hypertension, and vascular diseases | Not provided | Hydralazine, reserpine, chlorthalidone, and metoprolol |
| NCT02050529 | Recruiting participants | Hypertension, Pregnancy induced | 180 (estimated enrollment) | Hydralazine, labetalol |
| NCT01538875 | Completed | Hypertension, Pregnancy induced | 261 | Hydralazine, labetalol |
| NCT00383799 | Unknown | Ventricular tachycardia | 302 (estimated enrollment) | Procainamide, amiodarone |
| NCT00000464 | Completed | Arrhythmia, Cardiovascular diseases | 115 | Procainamide, quinidine, disopyramide, and other drugs |
| NCT00702117 | Completed | Atrial fibrillation, tachycardia | 123 | Procainamide, ajmaline, flecainide |
| NCT00589303 | Terminated | Atrial fibrillation, heart failure | 27 | Rhythm control drugs: Procainamide and other drugs |
| NCT00000556 | Completed | Arrhythmia, atrial fibrillation, cardiovascular diseases | 4060 | Procainamide and other drugs |
| NCT01205529 | Recruiting | Atrial fibrillation | 750 (estimated enrollment) | Procainamide |