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. 2016 Feb 24;11(2):e0150132. doi: 10.1371/journal.pone.0150132

Fig 7. Activation of integrin αvβ3 alone is not sufficient for generating a migration and invasion-permissive ECM.

Fig 7

A) Quantitative assessment of migration directionality of MDA-MB-231 and MCF10DCIS.com cells within the ECMs from HMF mock and Sdc1 cells treated with control or β3 clasp peptide using time-lapse microscopy. Columns labeled with different letters are significantly different (p<0.001). B) Invasion of MDA-MB-231 and MCF10DCIS.com cells through ECMs from HMF mock and Sdc1 cells treated with control or β3 clasp peptide. Columns labeled with different letters are significantly different (at least p<0.05). Ctrl pep, control peptide; β3 pep, β3 clasp peptide.