Table 1.
Demographic data for HYPO and control groups.
| HYPOa (n = 22) | Control (n = 24) | p-value | |
|---|---|---|---|
| Age (years) | 10.3 (0.6) | 10.5 (0.71) | 0.28 |
| Sex (male/female) | 14/8 | 15/9 | |
| Socioeconomic statusb | 1.86 (0.77) | 1.83 (0.86) | 0.9 |
| Handedness (right/left)c | 21/1 | 23/1 | |
| Full Scale IQ | 113.1 (12.6) | 116.8 (10.2) | 0.27 |
| Intracranial volume | 1774.5 (180.5) | 1750.0 (152.5) | 0.4 |
| TSH (mU/l)d | |||
| Trimester 1 | 8.70 (6.71) | ||
| Trimester 2 | 6.30 (8.50) | ||
| Trimester 3 | 3.24 (4.17) | ||
| Free T4 (nmol/L)e | |||
| Trimester 1 | 11.05 (2.65) | ||
| Trimester 2 | 13.02 (2.17) | ||
| Trimester 3 | 12.54 (2.15) | ||
| Thyroxine dosage (μg/day) | 103.5 (41.8) | ||
| Range | 50–200 |
aThis number represents the remaining sample after the two cases with unacceptable scans were eliminated.
bBased on Hollingshead and Redlich’s (1975) 5-point rating scale for socioeconomic status (SES) derived from occupations and educational levels of both parents; this information was ascertained from a case-history questionnaire given to parents. A rating value of 1 signifies the highest SES level and of 5, the lowest.
cBased on a 10-item questionnaire completed during by children during the neuropsychological assessment.
dBased on 21 women for trimester 1, 19 for trimester 2, and 16 for trimester 3; values elevated in all trimesters.
eBased on 14 women for trimester 1, 12 for trimester 2, and 10 for trimester 3; values low but not significantly so for each trimester.