Table 4.
Regions showing significant correlations (p < 0.01) between maternal TSH values by trimester and vertex-based cortical thickness results for entire HYPO group.
| Region | Lobe | Effect | Coordinates | Number of vertices | Cluster-wise p-value |
|---|---|---|---|---|---|
| Trimester 1 | |||||
| L Precentral sulcus | Frontal | Thickening | −15, −13, 60 | 91 | 0.004 |
| R Supramarginal gyrus | Parietal | Thickening | 46, −26, 24 | 93 | 0.005 |
| R Supramarginal gyrus | Parietal | Thickening | 53, −39, 35 | 68 | 0.006 |
| R Cuneus | Occipital | Thickening | 7, −84, 20 | 43 | 0.005 |
| Trimester 2 | |||||
| L Precentral gyrus | Frontal | Thickening | −33, −16, 62 | 111 | 0.0002 |
| R Postcentral sulcus | Parietal | Thickening | 28, −39, 51 | 131 | 0.0002 |
| R Cuneus | Occipital | Thickening | 8.5, −84, 19 | 64 | 0.0002 |
| Trimester 3 | |||||
| L Pericallosal sulcus | Temporal | Thinning | −6, 11, 24 | 99 | 0.008 |
| R Inferior angular gyrus | Parietal | Thinning | 44, −65, 30 | 58 | 0.007 |
| L Precentral sulcus | Frontal | Thickening | −15, 12, 59 | 91 | 0.003 |
| R Postcentral sulcus | Parietal | Thickening | 28, −39, 51.5 | 135 | 0.002 |
| L Inferior occipital gyrus/sulcus | Occipital | Thickening | −31, −86, −1 | 42 | 0.008 |
| R Cuneus | Occipital | Thickening | 12, −86, 18 | 53 | 0.008 |
Values in bold italics indicate relationship maintained through three trimesters and in italics only, relationship maintained in two consecutive trimesters.