Table 2.
Clinical characteristics of pregnant women with syphilis infection in China in 2013, by regiona.
| Characteristic | Total | Region | P value | ||
|---|---|---|---|---|---|
| Eastern | Central | Western | |||
| History of syphilis infection | |||||
| Yes | 2910 (18.3%) | 1537 (23.2%) | 566 (14.9%) | 807 (14.8%) | <0.001 |
| No | 12974 (81.7%) | 5082 (76.8%) | 3232 (85.1%) | 4660 (85.2%) | |
| Maternal syphilis stage | |||||
| Latent syphilis | 10742 (67.6%) | 4751 (71.8%) | 2193 (57.7%) | 3798 (69.5%) | <0.001 |
| Primary syphilis | 981 (6.2%) | 421 (6.4%) | 234 (6.2%) | 326 (6.0%) | |
| Secondary syphilis | 158 (1.0%) | 81 (1.2%) | 48 (1.3%) | 29 (0.5%) | |
| Tertiary syphilis | 73 (0.5%) | 39 (0.6%) | 17 (0.4%) | 17 (0.3%) | |
| Unknown | 3930 (24.7%) | 1327 (20.0%) | 1306 (34.4%) | 1297 (23.7%) | |
| Period of maternal syphilis detection | |||||
| During pregnancy | 8829 (55.6%) | 4136 (62.5%) | 1728 (45.5%) | 2965 (54.2%) | <0.001 |
| At delivery | 5246 (33.0%) | 1675 (25.3%) | 1619 (42.6%) | 1952 (35.7%) | |
| Postpartum | 1722 (10.8%) | 771 (11.6%) | 430 (11.3%) | 521 (9.5%) | |
| Other | 87 (0.5%) | 37 (0.6%) | 21 (0.6%) | 29 (0.5%) | |
| Maternal titer of nontreponema | |||||
| ≤1 : 4 | 11118 (70.0%) | 4780 (72.2%) | 2587 (68.1%) | 3751 (68.6%) | <0.001 |
| 1 : 8–1 : 32 | 3736 (23.5%) | 1405 (21.2%) | 1006 (26.5%) | 1325 (24.2%) | |
| ≥1 : 64 | 565 (3.6%) | 261 (3.9%) | 111 (2.9%) | 193 (3.5%) | |
| Unknown | 465 (2.9%) | 173 (2.6%) | 94 (2.5%) | 198 (3.6%) | |
| Gestational week for the first treatment | |||||
| ≤14 | 1972 (12.4%) | 1033 (15.6%) | 297 (7.8%) | 642 (11.7%) | <0.001 |
| 15–28 | 3151 (19.8%) | 1498 (22.6%) | 500 (13.2%) | 1153 (21.1%) | |
| 29–37 | 1966 (12.4%) | 815 (12.3%) | 388 (10.2%) | 763 (14.0%) | |
| >37 or untreated | 8795 (55.4%) | 3273 (49.4%) | 2613 (68.8%) | 2909 (53.2%) | |
| Drug of treatment | |||||
| Penicillin | 9386 (59.1%) | 3940 (59.5%) | 1785 (47.0%) | 3661 (67.0%) | <0.001 |
| Nonpenicillin | 485 (3.1%) | 253 (3.8%) | 99 (2.6%) | 133 (2.4%) | |
| Untreated | 6013 (37.9%) | 2426 (36.7%) | 1914 (50.4%) | 1673 (30.6%) | |
| Syphilis testing of husband/sexual partner | |||||
| Negative | 3654 (23.0%) | 1616 (24.4%) | 890 (23.4%) | 1148 (21.0%) | <0.001 |
| Positive | 1302 (8.2%) | 542 (8.2%) | 275 (7.2%) | 485 (8.9%) | |
| Untested/unknown | 10928 (68.8%) | 4461 (67.4%) | 2633 (69.3%) | 3834 (70.1%) | |
aValues are given as number (percentage) unless otherwise indicated.