Table 2. Rate of YFP Quenching and Quenching (%) for FRT-CFTR-hsYFP cells.

	Rate of Quenching (k)	Significance vs Control	Significance vs NPS-R568	Quench after 5 min (%)	Significance vs Control	Significance vs NPS-R568
Control	0.42 ± 0.02			78 ± 3			N = 7, n =197
1 μM NPS-R568	1.31 ± 0.03	p < 0.001		61 ± 3	p < 0.001		N = 9, n = 168
1 μM NPS-R568 + 10 μM Inh-172	0.42 ± 0.03	NS	p < 0.001	83 ± 1	NS	p < 0.01	N = 8, n = 132
1 μM NPS-R568 + 25 μM MDL-12330A	0.56 ± 0.05	p < 0.001	p < 0.001	78 ± 3	NS	p < 0.01	N = 6, n = 93
20 μM Forskolin	1.76 ± 0.05	p < 0.001	p < 0.001	46 ± 2	p < 0.001	p < 0.001	N = 10, n = 150