Table 1. Concentration of tolcapone in human plasma samples from treated individuals.

Subject	Tolcapone dose	Basal sample	Dosed sample*
Subject HV1	200 mg	<0.2 μg ml−1	3.7 μg ml−1 (13.6 μM)
Subject HV2	2 × 200 mg	<0.2 μg ml−1	20.6 μg ml−1 (75.6 μM)

^*Dosed sample corresponds to plasma collected 2 h after drug administration (Tmax).