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. 2016 Feb 25;6:22094. doi: 10.1038/srep22094

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Copyright © 2016, Macmillan Publishers Limited

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Neutralising antibody responses following IPV2 immunisation; (a) 21 days post priming; (b) 21 days post boost 1; (c) 21 days post boost 2; and (d) Seropositivity of each group to IPV2 immunisation over time, (seropositivity being defined as a neutralisation titre ≥3.0 log₂ (dotted line)). Each symbol represents a single animal, with the line indicating the median titre. **indicates a statistically significant (p = <0.01) difference between dose matched Nanopatch and IM group as assessed by one-way ANOVA (alpha level 0.05) with a Tukey post test.