Table 1.
Principal characteristics of the included studies
| Study | Year | Center, city, country | Type of publication | Time interval considered | Number of lesions | Indication for EMR or ESD | Definition of complete resection |
|---|---|---|---|---|---|---|---|
| Iizuka | 2009 | Maebashi Red Cross Hospital, Maebashi, Japan | Full-text | January 2000–December 2004 | 121 | LST ≥20 mm | One-piece resection with histopathologically tumor-free margins, i.e. at least 0.5 mm between the tumor edge and the margin |
| Kobayashi | 2009 | Tochigi Cancer Center Hospital, Tochigi, Japan | Abstract | January 2000–June 2007 | 147 | ESD: LST-NG lesions ≥20 mm and LST-G lesions ≥30 mm EMR/EPMR: LST-G lesions ≥20 mm and ≤30 mm | NA |
| Nakae | 2010 | Juntendo University School of Medicine, Tokyo, Japan | Abstract | January 1995–December 2008 | 251 | LST ≥20 mm | NA |
| Saito | 2010 | National Cancer Center Hospital, Tokyo, Japan | Full-text | January 2003–December 2006 | 373 | ESD: LST-NG lesions ≥20 mm and LST-G lesions ≥40 mm EMR/EPMR: LST-G lesions ≥20 mm and ≤40 mm | NA |
| Tajika | 2011 | Aichi Cancer Center Hospital, Nagoya, Japan | Full-text | January 1995–December 2009 | 212 | LST ≥20 mm | Lateral and vertical margins both negative for tumor cells |
| Terasaki | 2011 | Hiroshima University Hospital, Hiroshima, Japan | Full-text | April 2006–December 2009 | 239 | ESD: lesions ≥20 mm unsuitable for en bloc resection by snare EMR; LST-NG; type VI pit pattern; cancer with submucosal infiltration; large depressed-type tumor fibrosis caused by biopsy or peristalsis of the lesions; local residual early cancer after endoscopic resection; sporadic localized tumors in chronic inflammation, such as ulcerative colitis. | NA |
| Sudo | 2011 | Northern Yokohama Hospital, Yokohama, Japan | Abstract | NA | 676 | LST ≥20 mm | NA |
| Lee | 2012 | Daehang Hospital, Seoul, Korea | Full-text | January 2004–November 2009 | 523 | LST ≥20 mm | Mucosal and submucosal margins of a specimen both free of adenoma and adenocarcinoma |
| Coumaros | 2012 | Clinique Sainte Barbe, Strasbourg, France | Abstract | 2005–2010 | 112 | LST ≥20 mm | NA |
| Kang | 2012 | Bongseng Memorial Hospital, Busan, Korea | Abstract | February 2009–March 2011 | 57 | LST ≥20 mm | NA |
| Kudo | 2013 | Showa University Northern Yokohama, Japan | Abstract | April 2011–December 2012 | 1922 | LST ≥20 mm | NA |
EMR: endoscopic mucosal resection; ESD: endoscopic submucosal dissection; LST-NG: non-granular laterally spreading tumors; LST-G: granular laterally spreading tumors.