Table 2.
Characteristics of patients treated by endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR)
| Study | Treatment | Number of lesions | Mean age in years ± SD (range) | Male/Female | EUS reported (yes/no) | Instruments | Injection solution | Mean follow-up months ± SD (range) |
|---|---|---|---|---|---|---|---|---|
| Iizuka | ESD | 44 | 69 ± 12 (34–86) | 24/20 | Yes | Flex knife | Sodium hyaluronate | NA |
| EMR | 83 | 66 ± 12 (32–91) | 242/140 | Yes | NA | |||
| Kobayashi | ESD | 27 | NA | NA | No | NA | NA | NA |
| EMR | 120 | NA | NA | No | NA | |||
| Nakae | ESD | 86 | NA | NA | No | NA | NA | NA |
| EMR | 165 | NA | NA | No | NA | NA | ||
| Saito | ESD | 145 | 64 ± 11 | NA | No | B-knife, IT-knife | Sodium hyaluronate, glycerol | 20 ± 13 (6–61) |
| EMR | 228 | 64 ± 4 | NA | No | Sodium hyaluronate | 26 ± 17 (6–68) | ||
| Tajika | ESD | 96 | 64.3 ± 9.2 | 49/36 | No | B-knife | Sodium hyaluronate or saline | 14.3 ± 13.4 (3–53) |
| EMR | 116 | 59.9 ± 10.6 | 61/39 | No | Saline | 53.8 ± 44.6 (3–191) | ||
| Terasaki | ESD | 91 | 66.7 ± 10.7 (42–86) | 38/23 | No | Dual knife, Flex knife, Hook knife, SB knife Jr | Sodium hyaluronate | NA |
| EMR | 178 | 67.9 ± 11.3 (39–89) | 99/79 | No | Glycerol | NA | ||
| Sudo | ESD | 167 | NA | NA | No | NA | NA | NA |
| EMR | 509 | NA | NA | No | NA | NA | ||
| Lee | ESD | 314 | 61 (25–85) | NA | No | Flex knife, Hook knife | Sodium hyaluronate, saline | 17 |
| EMR | 209 | 63 (23–90) | NA | No | Glycerol or saline | 26 | ||
| Coumaros | ESD | 46 | NA | NA | No | NA | NA | NA |
| EMR | 66 | NA | NA | No | NA | NA | ||
| Kang | ESD | 16 | NA | NA | No | NA | NA | 4.9 ± 3.7 (3–16) |
| EMR | 50 | NA | NA | No | NA | 6.1 ± 5.0 (3–24) | ||
| Kudo | ESD | 485 | NA | NA | No | NA | NA | NA |
| EMR | 1437 | NA | NA | No | NA | NA |
EUS: endoscopic ultrasound.