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. 2016 Feb 25;6:21785. doi: 10.1038/srep21785

Figure 6. Quantification using FMT of LO1-750 and MMPSense targeting in mice in relation to duration of diet.

Figure 6

Group I were fed a high fat diet for 30 weeks; Group II were fed a HF diet for 30 weeks followed by 12 weeks on chow; and Group III were fed a high fat diet for 42 weeks. Each mouse received 50 μg LO1-750 and 2.4 nmol MMPSense by iv injection and was imaged after 4 hours (A) demonstrates significantly more LO1-750 uptake in Group III vs. Group I, with a clear linear trend between the three groups (R square 0.42; p = 0.004); (B) shows that MMPSense gave a similar difference between Groups I and III but a weaker linear trend overall (R square 0.29; p = 0.02). Each group was composed of six mice.