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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Gastrointest Endosc. 2015 Mar;81(3):700–709.e3. doi: 10.1016/j.gie.2014.10.033

Table 1.

Summary of the clinical outcomes-based evidence for CRC screening tests.

Observational studies Randomized trials
Number of studies Participants Magnitude of benefit Number of trials Participants Magnitude of benefit
Colonoscopy 8 1,290,544 Highest 0 0 N/A
Sigmoidoscopy 3 21,950 High 4 414,966 High
Guaiac-FOBT 13 900,843 Moderate 4 329,642 Moderate
CTC 0 0 N/A 0 0 N/A
FIT 0 0 N/A 0 0 N/A
Stool DNA tests 0 0 N/A 0 0 N/A

FOBT - fecal occult blood testing; CTC – computed tomography colonography; DNA – deoxyribonucleic acid; N/A – not applicable.