Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 25;35:37. doi: 10.1186/s13046-016-0311-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Wang et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 7 — Regulation of the p15 and p27 promoter occupancy on their promoters region by KDM5B. a and b The KDM5B occupancy and trimethylation status of histone H3 (H3K4Me3) at the promoters of p15 and p27 genes. C and R: Control siRNA and KDM5B siRNA, respectively. ChIP was used to precipitate KDM5B and H3K4Me3-bound DNA followed by PCR amplification with the specific primers spanning p15 and p27 promoters. Input: 2 % of total chromatin materials were PCR amplified with the same primers