Table 1.
Clinicopathological features | n | KDM5B | ||
---|---|---|---|---|
High expression (≥Median) |
Low expression (<Median) |
P-value | ||
Gender | ||||
Male | 65 | 34 | 31 | 0.6753 |
Female | 35 | 16 | 19 | |
Age (years) | ||||
≥ 50 | 60 | 32 | 28 | 0.5406 |
< 50 | 40 | 18 | 22 | |
Tumor size (cm) | ||||
≥ 5 | 55 | 36 | 19 | 0.0012** |
< 5 | 45 | 14 | 31 | |
Tumor number | ||||
Solitary | 62 | 33 | 29 | 0.5368 |
Multiple | 38 | 17 | 21 | |
HBsAg | ||||
Positive | 76 | 40 | 36 | 0.4829 |
Negative | 24 | 10 | 14 | |
HCV | ||||
Positive | 11 | 8 | 3 | 0.1997 |
Negative | 89 | 42 | 47 | |
Cirrhosis | ||||
Positive | 82 | 43 | 39 | 0.4356 |
Negative | 18 | 7 | 11 | |
ALT (U/L) | ||||
≥ 45 | 46 | 26 | 20 | 0.3158 |
< 45 | 54 | 24 | 30 | |
AFP (ng/ml) | ||||
≥ 20 | 57 | 31 | 26 | 0.4193 |
< 20 | 43 | 19 | 24 | |
TNM stage | ||||
I + II | 56 | 21 | 35 | 0.0085** |
III + IV | 44 | 29 | 15 | |
Edmondson grade | ||||
I + II | 59 | 23 | 36 | 0.0142* |
III + IV | 41 | 27 | 14 |
The median expression level of KDM5B was used as the cut off
*P < 0.05
**P < 0.01 between the two groups