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. 2016 Feb 25;35:37. doi: 10.1186/s13046-016-0311-5

Table 1.

Correlation between KDM5B expression and clinicopathological features in HCC

Clinicopathological features n KDM5B
High expression
(≥Median)
Low expression
(<Median)
P-value
Gender
 Male 65 34 31 0.6753
 Female 35 16 19
Age (years)
  ≥ 50 60 32 28 0.5406
  < 50 40 18 22
Tumor size (cm)
  ≥ 5 55 36 19 0.0012**
  < 5 45 14 31
Tumor number
 Solitary 62 33 29 0.5368
 Multiple 38 17 21
HBsAg
 Positive 76 40 36 0.4829
 Negative 24 10 14
HCV
 Positive 11 8 3 0.1997
 Negative 89 42 47
Cirrhosis
 Positive 82 43 39 0.4356
 Negative 18 7 11
ALT (U/L)
  ≥ 45 46 26 20 0.3158
  < 45 54 24 30
AFP (ng/ml)
  ≥ 20 57 31 26 0.4193
  < 20 43 19 24
TNM stage
 I + II 56 21 35 0.0085**
 III + IV 44 29 15
Edmondson grade
 I + II 59 23 36 0.0142*
 III + IV 41 27 14

The median expression level of KDM5B was used as the cut off

*P < 0.05

**P < 0.01 between the two groups