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. 2016 Feb 24;18:54. doi: 10.1186/s13075-016-0953-x

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© Muratovic et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Comparison of cartilage volume (a), Osteoarthritis Research Society International; (OARSI) grades (b), cartilage tidemark progression (arrows identify tidemarks) (c), penetration of vascular cones (circled) (d). Histopathology of bone marrow; bone marrow edema (e), fibrosis (f), necrosis (g), thick-walled arterioles (h) and fibrovascular cystic formation (i). Represented histologically and graphically for specimens with no bone marrow lesions evident (No BML), bone marrow lesions evident only in fast spin-echo proton density-weighted (PDFS) sequences (BML 1), and bone marrow lesions evident in both PDFS and T1-weighted sequences (BML 2): *p = 0.05, **p = 0.005, ***p = 0.0005