Table 2.
Histological findings in the no BML and BML groups
| No BML (n = 12) | BML (1 + 2) (n = 44) | P value | |
|---|---|---|---|
| TM, number/mm2 a | 2 (2, 3) | 3 (3, 4) | <0.0001 |
| Vascular cones, number/mm2 b | 0.12 ± 0.07 | 0.20 ± 0.12 | 0.004 |
| Edema | 0.006 | ||
| Score 1 (<5 %) | 83 % | 41 % | |
| Score 2 (5–14 %) | 17 % | 31.8 % | |
| Score 3 (15–24 %) | - | 20.4 % | |
| Score 4 (25–50 %) | - | 6.8 % | |
| Score 5 (>50 %) | - | - | |
| Fibrosis | 0.4 | ||
| Score 1 (<5 %) | 75 % | 66 % | |
| Score 2 (5–14 %) | 25 % | 16 % | |
| Score 3 (15–24 %) | - | 11 % | |
| Score 4 (25–50 %) | - | 7 % | |
| Score 5 (>50 %) | - | - | |
| Necrosis | 0.002 | ||
| Score 1 (<5 %) | 33.1 % | 9 % | |
| Score 2 (5–14 %) | 66.6 % | 41 % | |
| Score 3 (15–24 %) | - | 41 % | |
| Score 4 (25–50 %) | - | 6.8 % | |
| Score 5 (>50 %) | - | 2.2 % | |
| Th. wall Art., number/mm2 a | 0.07 (0.06, 0.1) | 0.2 (0.1, 0.4) | <0.0001 |
| Fibrovascular c., number/mm2 a | 0 (0 %) | 0 (0, 0.2) | 0.01 |
aValues presented with median (25th, 75th percentiles). bValues presented with mean ± standard deviation. P values are for difference between the group with no bone marrow lesions (No BML) and the group with BML (BML 1 + BML 2). TM tidemark duplications, Vascular cones vascular cones penetrating from subchondral bone into calcified cartilage, Th. wall Art thick-walled arterioles present in marrow, Fibrovascular c. fibrovascular cystic formations