Table 4.
Group with no bone marrow lesions (No BML) vs. groups with BML 1 and BML 2
| No BML vs. BML 1 | No BML vs. BML 2 | |
|---|---|---|
| Cartilage | ||
| MRI cartilage volume | Not different | Low |
| OARSI histology score | High | High |
| Bone marrow pathology | ||
| Edema | Not different | High |
| Fibrosis | Not different | High |
| Necrosis | Not different | High |
| Vascularity | High | High |
| Subchondral bone | ||
| Plate thickness | High | Very high |
| Trabecular bone volume | Not different | High |
| Osteoid volume and thickness | Not different | High |
Changes at tissue level between the No BML group vs. group with BML detected using the fast spin-echo proton density-weighted sequence only, with absent signal on T1-weighted sequence in the same area (BML 1) and the group with BML detected by both fast spin-echo proton density-weighted and T1 sequences (BML 2). MRI magnetic resonance imaging, OARSI Osteoarthritis Research Society International