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. Author manuscript; available in PMC: 2016 Aug 23.
Published in final edited form as: Circulation. 2016 Feb 23;133(8):742–755. doi: 10.1161/CIRCULATIONAHA.115.008721

Table 1.

Barriers to evidence-based cardiovascular disease health care at the patient, health-care provider and health system/policy level, prioritized by country income strata.

Barrier Example Country Income Strata
Patient 18:
Availability, access, and costs (External) Lack of health insurance Both HIC and LMIC
Knowledge (Internal) Asymptomatic thus question need for ongoing treatment Both HIC and LMIC
Beliefs (Internal) Alternative/traditional medicine LMIC > HIC
Memory (Internal) Affects adherence to recommended therapies Both HIC and LMIC
Side effects to medications (Internal) Whether real or perceived (myalgia, cough, etc.) Both HIC and LMIC
Health Care Provider 18, 21:
Knowledge Familiarity and awareness of management options LMIC: Standards of education, ongoing options for continued medical education
Attitudes Lack of agreement with guidelines, outcome expectancy, self-efficacy, motivation and treatment inertia LMIC: Conflicting opinions regarding alternative medicine
Behavior External or environmental factors limiting management (time, resources, reimbursement) LMIC>HIC
Health System/Policy 22:
Health Care Financing System Low priority in national budgets: competing political agendas (military, other medical conditions such as HIV, etc.). Limited universal health care coverage. LMIC>HIC
Medical Products and Technologies Lacking infrastructures for stocking pharmacies with evidence-based generic medications. Poor affordability of essential medications, even when they are generic. LMIC>HIC
Leadership/Governance Low Priority for cardiovascular disease prevention: lack of effective screening programs, smoking cessation programs, safe environments for exercise, high costs for healthy foods Both HIC and LMIC
Health Workforce Limited number of adequately trained physicians and health care professionals LMIC>HIC
Health Information System and Research Limited health system infrastructures to ensure monitoring of health determinants, performance and health status LMIC>HIC
Service Delivery Efficient delivery of effective and safe interventions Both HIC and LMIC

HIC=high-income countries; LMIC=low- and middle-income countries.