Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
During S phase, Eco1 acetylates Smc3. This reaction is required for the establishment of sister chromatid cohesion. In G2/M phases, cohesion has been established, and we propose that Smc3 acetylation may act to stabilize it. At the metaphase-to-anaphase transition, separase cleavage of Scc1 allows Hos1 to deacetylate Smc3.
