Table 1.

Patient’s characteristics and baseline tumor features

		Standard CRT	Extended CRT	p
N		99	12
Gender (M-F)		47 – 52 (47.5 – 52.5)	7 – 5 (58.3 – 41.7)	0.48
Age (years)		60.3 ± 12.7	58.6 ± 8.4	0.53
Tumor size (mm)		43.2 ± 11.6	43.3 ± 6.5	0.96
Distance anal verge (cm)		3.9 ± 2.0	4.6 ± 1.3	0.13
Initial Staging
cT	2	6 (6.1 %)	5 (41.7 %)
	3	87 (87.9 %)	7 (58.3 %)
	4	6 (6.1 %)	0 (0.0 %)	0.001
cN	positive	43 (43.4 %)	8 (66.7 %)	0.11
cUICC	I	6 (6.1 %)	3 (25.0 %)
	II	50 (50.5 %)	1 (8.3 %)
	III	43 (43.4 %)	8 (66.7 %)	0.006
TRG 3 or 4		22 (30.1 %)	3 (75.0 %)	0.09
CR (cCR or pCR)		23 (23.2 %)	8 (66.7 %)	0.004
Final tumor size (mm)		40.6 ± 22.2	26.4 ± 7.9	0.01
Final Staging
UICC	CCR	16 (16.1 %)	7 (58.4 %)
	pCR	7 (7.1 %)	1 (8.3 %)
	I	14 (14.1 %)	1 (8.3 %)
	II	30 (30.3 %)	0 (0.0 %)
	III	19 (19.2 %)	2 (16.7 %)	0.004