Table 2. Comparison of the TCGA analyses of PD-L1 gene expression and is prognostic role in two recent studies [10, 12].
Parameter/study | Berghoff et al. [10] | Nduom et al. [12] | |
---|---|---|---|
Sample size | 446 | 194 | |
Assay | Agilent microarray | Illumina RNASeq | |
Significant OS correlation of PD-L1 gene expression | Univariate | No (HR = 1.038, 95% CI 0.9553 – 1.368, p = 0.144) | Yes (HR = 1.54, 95% CI 1.05 – 2.28, p = 0.0231) |
Multivariate (PD-L1, age) | No (HR = 1.036, 95% CI 0.8702 – 1.232, p = 0.694) | Yes (HR = 1.52, 95% CI 1.03 – 2.25, p = 0.0343) |