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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Pain. 2015 Jun;156(6):1153–1160. doi: 10.1097/j.pain.0000000000000171

Figure 4.

Figure 4

Effects of ketoprofen, morphine and U69,593 on nesting depressed by i.p. treatment with 0.32% lactic acid (Panel A), nesting depressed by unilateral I.pl. treatment with CFA (Panel B), or control nesting in the absence of any other treatment (Panel C). Panel D shows effects of ketoprofen and morphine on nesting depressed by treatment with U69,593. For each panel, the abscissa shows drug dose in mg/kg (log scale, V=vehicle), and the ordinate shows nesting expressed as Number of Zones Cleared. Different groups of 6–9 mice were used to determine each point. Filled points indicate significantly different from the associated vehicle treatment for that drug under that condition as determined by a significant 1-way ANOVA followed by the Dunnett’s post hoc test (p<0.05).