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. 2015 Aug 28;58(18):7501–7511. doi: 10.1021/acs.jmedchem.5b01033

Table 2. H2S Release Profiles of 1-(Benzoylthio)-3-phenylurea Based Donorsa.

graphic file with name jm-2015-010333_0017.jpg

      CysSH
GSH
donors R1 R2 Tpeak (min) [H2S]peak (μM) Tpeak (min) [H2S]peak (μM)
NSHD-27 H H 95 21.5 110 29.9
NSHD-28 OCH3 H 105 14.1 120 26.4
NSHD-29 CH3 H 105 16.5 130 20.0
NSHD-30 F H 75 18.8 90 18.5
NSHD-31 Cl H 95 18.2 120 24.9
NSHD-32 H CH3 90 21.8 130 27.4
NSHD-33 H Cl 110 10.7 120 20.9
a

Data were reported as the average value of three measurements.