TABLE 3.
Summary of statistically significant genetic association results for Agatston calcium score in MESA
| Group | SNP ID | HG 19 Position | Effect/Other Allele | EAFa | N | Beta | SE | P |
| All participants | rs7681334 | 185,710,859 | A/G | 0.497/0.450/ 0.647/0.944 | 3,852 | −0.126 | 0.043 | 0.003 |
| Participants without diabetes | rs7681334 | 185,710,859 | A/G | 0.496/0.452/ 0.644/0.928 | 3,172 | −0.157 | 0.046 | 0.001 |
| Participants without diabetes | rs4862423 | 185,726,548 | T/C | 0.407/0.270/ 0.499/0.658 | 3,172 | −0.150 | 0.048 | 0.002 |
Results are presented based on the basic model of genetic association including adjustment for age, gender, study site, and principal components of ancestry.
a
EAF for MESA shown separately for Caucasian/African American/Hispanic/Chinese participants.