TABLE 1.

Absolute values for endocannabinoids in WAT and BAT

	AEA (pmol/mg)	2-AG (pmol/mg)	PEA (pmol/mg)	OEA (pmol/mg)
BAT
Control	0.25 ± 0.04	0.93 ± 0.12	1.31 ± 0.16	1.95 ± 0.12
Acute CL	0.70 ± 0.17a	1.80 ± 0.43	3.31 ± 0.55a	4.16 ± 0.78a
Chronic CL	0.30 ± 0.06	0.78 ± 0.09	1.49 ± 0.21	2.39 ± 0.15a
Chronic and acute CL	0.54 ± 0.09a	1.78 ± 0.31a	3.33 ± 0.38c	5.68 ± 0.49c
1 day cold	0.50 ± 0.13	0.99 ± 0.06	3.19 ± 0.50b	4.35 ± 0.64b
7 day cold	0.32 ± 0.06	0.70 ± 0.13	1.96 ± 0.10b	2.99 ± 0.17c
WAT
Control	0.03 ± 0.003	0.30 ± 0.04	0.75 ± 0.10	0.67 ± 0.11
Acute CL	0.06 ± 0.007b	0.31 ± 0.06	1.08 ± 0.10a	1.06 ± 0.13a
Chronic CL	0.09 ± 0.010c	0.85 ± 0.07c	1.12 ± 0.13	1.37 ± 0.08c
Chronic and acute CL	0.11 ± 0.0013c	0.94 ± 0.10c	1.99 ± 0.30a	2.11 ± 0.23c
1 day cold	0.10 ± 0.0015c	0.40 ± 0.04	1.61 ± 0.15c	1.60 ± 0.08c
7 day cold	0.13 ± 0.0015c	0.52 ± 0.07a	2.31 ± 0.62a	1.92 ± 0.29b

Mice were treated as described in the legend of Fig. 2. The concentrations of 2-AG, AEA, PEA, and OEA were measured in BAT and WAT. Data are calculated as picomoles per milligram wet weight. Values are mean ± SEM.

^aP < 0.05, Student’s t-test.

^bP < 0.01, Student’s t-test.

^cP < 0.001, Student’s t-test.