TABLE 1.
Gene categories enriched in genes regulated by the gut microbiota during lard and fish oil diet
GO | Term | Fold Enrichment | FDR (Adjusted P value) |
Enriched in genes induced by the gut microbiota in mice fed lard | |||
— | — | — | — |
Enriched in genes reduced by the gut microbiota in mice fed lard | |||
16126 | Sterol biosynthetic process | 30.4 | 1.31E-09 |
6695 | Cholesterol biosynthetic process | 36.0 | 1.67E-09 |
8202 | Steroid metabolic process | 8.7 | 3.36E-08 |
16125 | Sterol metabolic process | 14.0 | 3.17E-08 |
8203 | Cholesterol metabolic process | 14.2 | 1.42E-07 |
6694 | Steroid biosynthetic process | 14.0 | 1.38E-07 |
8610 | Lipid biosynthetic process | 4.9 | 5.25E-05 |
7155 | Cell adhesion | 3.4 | 1.36E-04 |
22610 | Biological adhesion | 3.4 | 1.24E-04 |
8299 | Isoprenoid biosynthetic process | 18.8 | 1.40E-02 |
6720 | Isoprenoid metabolic process | 10.1 | 2.98E-02 |
Enriched in genes induced by the gut microbiota in mice fed fish oil | |||
6955 | Immune response | 3.1 | 5.79E-03 |
Enriched in genes reduced by the gut microbiota in mice fed fish oil | |||
— | — | — | — |
Enriched in genes regulated by interaction between dietary lipids and gut microbiota | |||
6694 | Steroid biosynthetic process | 15.0 | 1.10E-04 |
8202 | Steroid metabolic process | 7.3 | 3.45E-03 |
16126 | Sterol biosynthetic process | 19.7 | 2.99E-02 |
30198 | Extracellular matrix organization | 8.2 | 4.15E-02 |