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. 2016 Mar;57(3):474–481. doi: 10.1194/jlr.M065847

TABLE 1.

Gene categories enriched in genes regulated by the gut microbiota during lard and fish oil diet

GO Term Fold Enrichment FDR (Adjusted P value)
Enriched in genes induced by the gut microbiota in mice fed lard
 —
Enriched in genes reduced by the gut microbiota in mice fed lard
 16126 Sterol biosynthetic process 30.4 1.31E-09
 6695 Cholesterol biosynthetic process 36.0 1.67E-09
 8202 Steroid metabolic process 8.7 3.36E-08
 16125 Sterol metabolic process 14.0 3.17E-08
 8203 Cholesterol metabolic process 14.2 1.42E-07
 6694 Steroid biosynthetic process 14.0 1.38E-07
 8610 Lipid biosynthetic process 4.9 5.25E-05
 7155 Cell adhesion 3.4 1.36E-04
 22610 Biological adhesion 3.4 1.24E-04
 8299 Isoprenoid biosynthetic process 18.8 1.40E-02
 6720 Isoprenoid metabolic process 10.1 2.98E-02
Enriched in genes induced by the gut microbiota in mice fed fish oil
 6955 Immune response 3.1 5.79E-03
Enriched in genes reduced by the gut microbiota in mice fed fish oil
 —
Enriched in genes regulated by interaction between dietary lipids and gut microbiota
 6694 Steroid biosynthetic process 15.0 1.10E-04
 8202 Steroid metabolic process 7.3 3.45E-03
 16126 Sterol biosynthetic process 19.7 2.99E-02
 30198 Extracellular matrix organization 8.2 4.15E-02