Table 6. Mouse Pharmacokinetics of Compound 44.
| dose (mg/kg) | route | Cl (mL/min/kg) | Vss (L/kg) | Tmax (h) | AUC (h ng/mL) | bioavailability (%) | T1/2 (h) |
|---|---|---|---|---|---|---|---|
| 0.2 | iv | 65 | 1.44 | 0.10 | 50.8 | NA | 0.31 |
| 0.5 | po | 0.25 | 7.4 | 6 |
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