Table 3.
Sensitivity, specificity and cut‐off levels for maximum enzymatic conversion capacity (Vmax) limited sampling
| Test parameter | Cut‐off level | Sensitivity (%) | Specificity (%) | npv% | ppv% |
|---|---|---|---|---|---|
| V max (mg h −1 *1.85 m −2 ) | 667 | 80 | 78 | 99 | 16 |
| U/DHU t = 120 min ratio | 2.4 | 80 | 98 | 99 | 67 |
| U t = 120 min (mg l −1 ) | 6.4 | 80 | 96 | 99 | 51 |
The uracil/dihydropyrimidine dehydrogenase ratio at t = 120 min (U/DHUt = 120 min) and U concentration at t = 120 min (Ut = 120 min) were derived from receiver operating characteristic curves. npv, negative predictive value; ppv, = positive predictive value.