Table 3.

Shown is a comparison of the performance of the SFA and RPA in determining the perfect self-energy (kcal/mole) for a series of five folded proteins. Optimization of a single HCT scale factor for each method removes systematic error as shown by the mean signed percent differences. However, the mean RPA unsigned percent difference of 0.5 is smaller than that of the SFA.

	Self-Energy			Signed % Difference		Unsigned % Difference
	PMPB	SFA	RPA	SFA	RPA	SFA	RPA
CRN	−8141	−8191	−8196	−0.6	−0.7	0.6	0.7
ENH	−11919	−11852	−11878	0.6	0.3	0.6	0.3
FSV	−6254	−6341	−6287	−1.4	−0.5	1.4	0.5
PGB	−11794	−11743	−11803	0.4	−0.1	0.4	0.1
VII	−7206	−7132	−7133	1.0	1.0	1.0	1.0
Mean				0.0	0.0	0.8	0.5