Table 3.
Surface expression of five gene products on β7+ versus β7- CD4+ T cells
| Mean surface protein expression* | |||||
| Gene | Fold difference: Transcript** | Fold difference: Surface protein*** | CD45RA- β7+ cells | CD45RA- β7- cells | CD45RA+ cells |
| LAIR1 | +1.7 | +2.5 (+1.6 to +3.9) | 34.6 | 15.3 | 37.3 |
| KLRB1 | +1.7 | +2.5 (+2.2 to +3.6) | 26.1 | 10.7 | 1.1 |
| KLRG1 | +1.5 | 1.0 (-3.2 to +2.1) | 17.7 | 15.6 | 9.1 |
| NT5E | +1.3 | +1.7 (+1.2 to +3.2) | 20.3 | 11.7 | 6.8 |
| SELL | -1.8 | -1.8 (-2.1 to -1.5) | 22.8 | 40.2 | 50.7 |
* Mean fluorescence intensity (MFI, in arbitrary units) was measured for 5–8 subjects.** As determined using DNA microarrays. *** Values represent mean (range) of the fold difference in MFI between CD45RA- β7+ cells and CD45RA- β7- cells for all subjects. Positive fold difference values indicate higher expression on β7+ cells and negative fold difference values indicate higher expression on β7- cells.