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. 2016 Feb 15;126(3):1052–1066. doi: 10.1172/JCI85271

Figure 2. EIF1AX mutations and EIF1AX-RAS co-occurrence in thyroid cancers.

Figure 2

(A) Distribution of EIF1AX mutations in thyroid cancers and other tumors (modified from ref. 1). (B) Oncoprints showing the co-occurrence of EIF1AX with RAS mutations in PTC from TCGA (top, n = 401), PDTCs from our study (middle, n = 84), and ATCs from our series and from (21) (bottom, n = 55). (C) Kaplan-Meier graph showing significantly shorter survival in EIF1AX-mutated PDTCs (log-rank P = 0.048). See Supplemental Table 6 for detailed clinical correlations.