Skip to main content
. 2016 Mar;356(3):596–603. doi: 10.1124/jpet.115.229997

Fig. 1.

Fig. 1.

Effects of the NPRA antagonist A71915 on intrathecal BNP-induced scratching. A71915 was intrathecally administered 10 minutes prior to BNP. Scratching bouts were observed immediately after intrathecal BNP up to 1 hour. Time course in 10-minute intervals (A, C) and dose response of total BNP-induced scratching bouts for 1 hour (B, D) are shown. Top panels (A, B) present the effects of BNP alone. Bottom panels (C, D) present the effects of A71915 on BNP-induced scratching bouts. (E) Rotarod test was performed before and 10 minutes after administration of A71915. Each value represents mean ± S.E.M. (n = 6). ***P < 0.001 versus vehicle. #P < 0.05 versus vehicle/BNP.