TABLE 3.
Effects of centrally administered BB on cystometric parameters of single CMG
Data were calculated as the ratio to the pretreatment (before i.c.v.) control values presented as means ± S.E.M.
| Timing of evaluation | Vv | Rv | BC | VE |
|---|---|---|---|---|
| % of Control |
||||
| 0.03 nmol BB (n = 7) | ||||
| Before i.c.v. administration | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 | 100.00 ± 0.00 |
| After i.c.v. administration | ||||
| 20–30 min | 56.70 ± 3.94* | 89.51 ± 20.80 | 64.94 ± 6.19* | 92.93 ± 7.02 |
| 30–40 min | 65.34 ± 8.65* | 77.44 ± 3.53 | 67.66 ± 1.98* | 96.16 ± 2.01 |
| 40–50 min | 62.76 ± 5.08* | 92.40 ± 19.25 | 79.76 ± 8.55* | 94.61 ± 9.88 |
| 50–60 min | 104.40 ± 15.81 | 86.74 ± 17.55 | 88.58 ± 3.85 | 104.85 ± 8.93 |
P < 0.05 (compared with the respective parameters before administration by the Bonferroni method).