Fig. 3.

Effects of R(−)-MDPV, S(+)-MDPV, and MDPV on locomotor activity at an ambient temperature of 20°C (left) or 28°C (right) in mice. On the abscissae, SAL represents saline administration and numbers refer to doses of drug, expressed as milligram/kilogram on a log scale. The ordinate shows the mean total activity recorded over 6 hours postinjection, via radiotelemetry. Asterisks indicate significant differences between locomotor effects of drug doses and saline, within a given ambient temperature. Errors bars depict means ± S.E.M. IP, intraperitoneally.